• Skip to primary navigation
  • Skip to main content
  • Skip to footer
jax-derm-logo

Jacksonville Dermatology & Cosmetic Surgery

Jacksonville Dermatology & Cosmetic Surgery

Appointment Request
Call (904) 420-7372
  • Treatments
    • Blue Light Treatment
    • Botox
    • Cheek Fillers
    • Chemical Peel
    • Cyst Removal
    • Dysport
    • Dermal Fillers
    • Earlobe Fillers
    • Earlobe Repair
    • Eyelid Surgery
    • Hand Rejuvenation
    • Kybella®
    • Lip Fillers
    • Lip Lift
    • Lipoma Removal
    • Microneedling
    • Mole removal
    • Non-Surgical Eyelid Lift
    • Non-Surgical Nose Job
    • Scar Treatment
    • Vein Treatments
  • Conditions
    • Acne
    • Age Spots
    • Aging
    • Crows Feet
    • Dark Under Eye Circles
    • Forehead Wrinkles
    • Frown Lines
    • Seborrheic Keratosis
    • Skin Tags
  • Team
  • Before and After
  • Blog
  • Contact
  • Online Payments

Risk factors and timing of subsequent cutaneous squamous cell carcinoma in patients with cutaneous squamous cell carcinoma: a retrospective cohort study

September 4, 2020 by Support Leave a Comment

Marla Rodriguez, BS • Brandon T. Beal, MD • Manisha Manmohan, MD • Isaac N. Briskin, MA • Thomas Knackstedt, MD • Allison T. Vidimos, MD, RPh

Published: August 26, 2020 DOI:https://doi.org/10.1016/j.jaad.2020.08.083

Abstract

Background

Information about the frequency and timing of subsequent cutaneous squamous cell carcinoma (cSCC), along with associated risk factors, is limited. However, this information is crucial to guide follow-up care for these patients.

Objective

Evaluate the risk and timing of subsequent cSCC in patients who presented with initial diagnosis of cSCC.

Methods

Retrospective review of IRB-approved single institution registry of invasive cSCC. All patients had at least two primary cSCCs diagnosed on two separate dates 2-months apart.

Results

299 primary cSCCs were included. 6-months from initial cSCC diagnosis, 18.06%(n=54) of patients developed subsequent cSCC; at 1-year 31.77%(n=94), 3-years 67.56%(n=202), and 5-years 87.96%(n=263) developed subsequent cSCC. Risk factors associated with subsequent cSCC include age at initial diagnosis (HR=1.02, 95% CI=[1.004, 1.027], p=0.008), T2 stage (HR=1.66, 95% CI=[1.07, 2.57], p=0.025), and poor tumor grade. Tumor grades well, moderate, and unknown have HRs of 0.21 (p = <0.001), 0.16 (p = <0.001), and 0.25 (p = 0.001), respectively.

Conclusions

Of patients that develop subsequent cSCC, 18.06% do so within 6-months and 31.77% do so within 1-year of initial cSCC diagnosis. Patients with advanced age, poor histologic differentiation, and AJCC T2 stage are at highest risk. Close clinical follow-up after initial diagnosis is recommended.

Filed Under: Published Work

Reader Interactions

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Footer

Jacksonville Dermatology & Cosmetic Surgery
6817 Southpoint Pkwy Ste 101
Jacksonville, FL 32216
Phone: (904) 420-7372
Fax: (904) 914-9231

We Accept Medicare

Copyright © 2023 · Jacksonville Dermatology & Cosmetic Surgery · Log in